Super Bug From Space

You'd Think It Was Sci-Fi

Bacteria sent out to outer space come back strong.
Yep. It's like a B- Movie Plot, but here it is.

The germ: Salmonella, best known as a culprit of food poisoning. The trip: Space Shuttle STS-115, September 2006. The reason: Scientists wanted to see how space travel affects germs, so they took some along — carefully wrapped — for the ride. The result: Mice fed the space germs were three times more likely to get sick and died quicker than others fed identical germs that had remained behind on Earth.

"Wherever humans go, microbes go, you can't sterilize humans. Wherever we go, under the oceans or orbiting the earth, the microbes go with us, and it's important that we understand ... how they're going to change," explained Cheryl Nickerson, an associate professor at the Center for Infectious Diseases and Vaccinology at Arizona State University.

Nickerson added, in a telephone interview, that learning more about changes in germs has the potential to lead to novel new countermeasures for infectious disease.

She reports the results of the salmonella study in Tuesday's edition of Proceedings of the National Academy of Sciences.

The researchers placed identical strains of salmonella in containers and sent one into space aboard the shuttle, while the second was kept on Earth, under similar temperature conditions to the one in space.

After the shuttle returned, mice were given varying oral doses of the salmonella and then were watched.

After 25 days, 40 percent of the mice given the Earth-bound salmonella were still alive, compared with just 10 percent of those dosed with the germs from space. And the researchers found it took about one-third as much of the space germs to kill half the mice, compared with the germs that had been on Earth.

The researchers found 167 genes had changed in the salmonella that went to space.

Why?

"That's the 64 million dollar question," Nickerson said. "We do not know with 100 percent certainty what the mechanism is of space flight that's inducing these changes."

However, they think it's a force called fluid shear.

"Being cultured in microgravity means the force of the liquid passing over the cells is low." The cells "are responding not to microgravity, but indirectly to microgravity in the low fluid shear effects."

"There are areas in the body which are low shear, such as the gastrointestinal tract, where, obviously, salmonella finds itself," she went on. "So, it's clear this is an environment not just relevant to space flight, but to conditions here on Earth, including in the infected host."

She said it is an example of a response to a changed environment.

"These bugs can sense where they are by changes in their environment. The minute they sense a different environment, they change their genetic machinery so they can survive," she said.

Worse the devil you know if it goes and come back from Space, then.

North West Passage Opens Up

A Strange Moment In History

The search for the North West Passage claimed many an explorer. Now, thanks to global warming, it's going to be relatively easy to navigate.

The European Space Agency said nearly 200 satellite photos this month taken together showed an ice-free passage along northern Canada, Alaska and Greenland, and ice retreating to its lowest level since such images were first taken in 1978.

The waters are exposing unexplored resources, and vessels could trim thousands of miles from Europe to Asia by bypassing the Panama Canal. The seasonal ebb and flow of ice levels has already opened up a slim summer window for ships.

Leif Toudal Pedersen, of the Danish National Space Center, said that Arctic ice has shrunk to some 1 million square miles. The previous low was 1.5 million square miles, in 2005.

"The strong reduction in just one year certainly raises flags that the ice (in summer) may disappear much sooner than expected," Pedersen said in an ESA statement posted on its Web site Friday.

Pedersen said the extreme retreat this year suggested the passage could fully open sooner than expected — but ESA did not say when that might be. Efforts to contact ESA officials in Paris and Noordwik, the Netherlands, were unsuccessful Saturday.

A U.N. panel on climate change has predicted that polar regions could be virtually free of ice by the summer of 2070 because of rising temperatures and sea ice decline, ESA noted.

Russia, Norway, Denmark, Canada and the United States are among countries in a race to secure rights to the Arctic that heated up last month when Russia sent two small submarines to plant its national flag under the North Pole. A U.S. study has suggested as much as 25 percent of the world's undiscovered oil and gas could be hidden in the area.

Environmentalists fear increased maritime traffic and efforts to tap natural resources in the area could one day lead to oil spills and harm regional wildlife.

Until now, the passage has been expected to remain closed even during reduced ice cover by multiyear ice pack — sea ice that remains through one or more summers, ESA said.

Researcher Claes Ragner of Norway's Fridtjof Nansen Institute, which works on Arctic environmental and political issues, said for now, the new opening has only symbolic meaning for the future of sea transport.

"Routes between Scandinavia and Japan could be almost halved, and a stable and reliable route would mean a lot to certain regions," he said by phone. But even if the passage is opening up and polar ice continues to melt, it will take years for such routes to be regular, he said.

"It won't be ice-free all year around and it won't be a stable route all year," Ragner said. "The greatest wish for sea transportation is streamlined and stable routes."

"Shorter transport routes means less pollution if you can ship products from A to B on the shortest route," he said, "but the fact that the polar ice is melting away is not good for the world in that we're losing the Arctic and the animal life there."

The opening observed this week was not the most direct waterway, ESA said. That would be through northern Canada along the coast of Siberia, which remains partially blocked.

Well, yeah. Aspirational targets for carbon emissions are nice, but I doubt the government would let me fill an Aspirational Tax Return, so I don't know why we have to be subjected to that kind of bullshit.